The herpes simplex virus virion host shutoff function.

The virion host shutoff (vhs) function of herpes simplex virus (HSV) limits the expression of genes in the infected cells by destabilizing both host and viral mRNAs. vhs function mutants have been isolated which are defective in their ability to degrade host mRNA. Furthermore, the half-life of viral...

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Bibliographic Details
Published in:J Virol
Main Authors: Kwong, A D, Frenkel, N
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.11.4834-4839.1989
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