Inhibition of human immunodeficiency virus replication by the herpes simplex virus virion host shutoff protein.

The herpes simplex virus (HSV) virion host shutoff gene (vhs) encodes a protein which nonspecifically accelerates the degradation of mRNA molecules, leading to inhibition of protein synthesis. This ability to inhibit a critical cellular function suggested that vhs could be used as a suicide gene in...

Full description

Saved in:
Bibliographic Details
Main Authors: Hamouda, T, McPhee, R, Hsia, S C, Read, G S, Holland, T C, King, S R
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191794/
https://ncbi.nlm.nih.gov/pubmed/9188626
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items