Herpes Simplex Virus Type 2 Virion Host Shutoff Protein Regulates Alpha/Beta Interferon but Not Adaptive Immune Responses during Primary Infection In Vivo

The herpes simplex virus (HSV) virion host shutoff (vhs) protein, the product of the UL41 (vhs) gene, is an important determinant of HSV virulence. vhs has been implicated in HSV interference with host antiviral immune responses, down-regulating expression of major histocompatibility complex molecul...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Murphy, Jenny A., Duerst, Rebecca J., Smith, Tracy J., Morrison, Lynda A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12915549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.17.9337-9345.2003
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