Herpes Simplex Virus Type 2 Virion Host Shutoff Protein Regulates Alpha/Beta Interferon but Not Adaptive Immune Responses during Primary Infection In Vivo

The herpes simplex virus (HSV) virion host shutoff (vhs) protein, the product of the UL41 (vhs) gene, is an important determinant of HSV virulence. vhs has been implicated in HSV interference with host antiviral immune responses, down-regulating expression of major histocompatibility complex molecul...

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Pubblicato in:	J Virol
Autori principali:	Murphy, Jenny A., Duerst, Rebecca J., Smith, Tracy J., Morrison, Lynda A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12915549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.17.9337-9345.2003
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