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Role of Herpes Simplex Virus ICP27 in the Degradation of mRNA by Virion Host Shutoff RNase
The virion host shutoff (VHS) RNase tegument protein released into cells by infecting virus has two effects. Preexisting stable mRNAs (e.g., GAPDH [glyceraldehyde-3-phosphate dehydrogenase]) are rapidly degraded. Stress response RNAs containing AU-rich elements (AREs) in the 3′ untranslated region (...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937800/ https://ncbi.nlm.nih.gov/pubmed/20631134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00975-10 |
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