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The Herpes Simplex Virus Host Shutoff RNase Degrades Cellular and Viral mRNAs Made before Infection but Not Viral mRNA Made after Infection

A herpes simplex virus tegument protein brought into the cell during infection and designated the virion host shutoff protein (VHS) is an endoribonuclease that degrades mRNA. The prevailing view for many years has been that the VHS-RNase does not discriminate between cellular and viral RNAs and that...

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書誌詳細
主要な著者: Taddeo, Brunella, Zhang, Weiran, Roizman, Bernard
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624343/
https://ncbi.nlm.nih.gov/pubmed/23388723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00005-13
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