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The Herpes Simplex Virus Host Shutoff RNase Degrades Cellular and Viral mRNAs Made before Infection but Not Viral mRNA Made after Infection

A herpes simplex virus tegument protein brought into the cell during infection and designated the virion host shutoff protein (VHS) is an endoribonuclease that degrades mRNA. The prevailing view for many years has been that the VHS-RNase does not discriminate between cellular and viral RNAs and that...

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Detaylı Bibliyografya
Asıl Yazarlar: Taddeo, Brunella, Zhang, Weiran, Roizman, Bernard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624343/
https://ncbi.nlm.nih.gov/pubmed/23388723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00005-13
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