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Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the U(L)47 tegument protein
Herpes simplex virus 1 (HSV-1) encodes an endoribonuclease that is responsible for the shutoff of host protein synthesis [virion host shutoff (VHS)-RNase]. The VHS-RNase released into cells during infection targets differentially four classes of mRNAs. Thus, (a) VHS-RNase degrades stable cellular mR...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645526/ https://ncbi.nlm.nih.gov/pubmed/23589852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305475110 |
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