Загрузка...

The Nuclear-Cytoplasmic Shuttling of Virion Host Shutoff RNase Is Enabled by pU(L)47 and an Embedded Nuclear Export Signal and Defines the Sites of Degradation of AU-Rich and Stable Cellular mRNAs

The herpes simplex virus host shutoff RNase (VHS-RNase) is the major early block of host responses to infection. VHS-RNase is introduced into cells during infection and selectively degrades stable mRNAs made before infection and the normally short-lived AU-rich stress response mRNAs induced by senso...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Shu, Minfeng, Taddeo, Brunella, Roizman, Bernard
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838220/
https://ncbi.nlm.nih.gov/pubmed/24109211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02603-13
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!