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Herpes Simplex Virus Virion Host Shutoff Protein Is Stimulated by Translation Initiation Factors eIF4B and eIF4H

The virion host shutoff protein (vhs) of herpes simplex virus triggers accelerated degradation of cellular and viral mRNAs while sparing other cytoplasmic RNA species. Previous work has shown that vhs forms a complex with translation initiation factor eIF4H, which displays detectable RNase activity...

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Detalhes bibliográficos
Main Authors: Doepker, Rosalyn C., Hsu, Wei-Li, Saffran, Holly A., Smiley, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387725/
https://ncbi.nlm.nih.gov/pubmed/15078951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4684-4699.2004
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