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The Virion Host Shutoff Endonuclease (UL41) of Herpes Simplex Virus Interacts with the Cellular Cap-Binding Complex eIF4F

The herpes simplex virus Vhs endonuclease degrades host and viral mRNAs. Isolated Vhs cuts any RNA at many sites. Yet, within cells, it targets mRNAs and cuts at preferred sites, including regions of translation initiation. Previous studies have shown that Vhs binds the translation factors eIF4A and...

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Detaylı Bibliyografya
Asıl Yazarlar: Page, Heidi G., Read, G. Sullivan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903273/
https://ncbi.nlm.nih.gov/pubmed/20427534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00166-10
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