Herpes Simplex Virus Virion Host Shutoff Protein Requires a Mammalian Factor for Efficient In Vitro Endoribonuclease Activity

The virion host shutoff protein (vhs) of herpes simplex virus (HSV) triggers global shutoff of host protein synthesis and accelerated mRNA turnover during virus infection and induces endoribonucleolytic cleavage of exogenous RNA substrates when it is produced in a rabbit reticulocyte (RRL) in vitro...

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Detalhes bibliográficos
Main Authors: Lu, Patricia, Jones, Frank E., Saffran, Holly A., Smiley, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114023/
https://ncbi.nlm.nih.gov/pubmed/11152490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1172-1185.2001
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