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Herpes Simplex Virus Virion Host Shutoff Protein Requires a Mammalian Factor for Efficient In Vitro Endoribonuclease Activity

The virion host shutoff protein (vhs) of herpes simplex virus (HSV) triggers global shutoff of host protein synthesis and accelerated mRNA turnover during virus infection and induces endoribonucleolytic cleavage of exogenous RNA substrates when it is produced in a rabbit reticulocyte (RRL) in vitro...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Lu, Patricia, Jones, Frank E., Saffran, Holly A., Smiley, James R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114023/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11152490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.3.1172-1185.2001
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