Herpes Simplex Virus Virion Host Shutoff Protein Is Stimulated by Translation Initiation Factors eIF4B and eIF4H

The virion host shutoff protein (vhs) of herpes simplex virus triggers accelerated degradation of cellular and viral mRNAs while sparing other cytoplasmic RNA species. Previous work has shown that vhs forms a complex with translation initiation factor eIF4H, which displays detectable RNase activity...

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Autores principales: Doepker, Rosalyn C., Hsu, Wei-Li, Saffran, Holly A., Smiley, James R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC387725/
https://ncbi.nlm.nih.gov/pubmed/15078951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4684-4699.2004
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