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The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNA

The herpes simplex virus virion host shutoff (vhs) RNase destabilizes cellular and viral mRNAs and blunts host innate antiviral responses. Previous work demonstrated that cells infected with vhs mutants display enhanced activation of the host double-stranded RNA (dsRNA)-activated protein kinase R (P...

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Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Dauber, Bianca, Saffran, Holly A., Smiley, James R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821131/
https://ncbi.nlm.nih.gov/pubmed/31626661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008111
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