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Pontin, a novel interactor of mutant p53 that promotes mutant p53 gain of function

Many tumor-associated mutant p53 proteins gain new activities to promote tumorigenesis, which is termed as gain of function of mutant p53 (GOF). Currently, the mechanisms of mutant p53 GOF remain elusive. We recently identified the AAA+ ATPase pontin as a critical regulator of mutant p53 GOF, thus p...

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書誌詳細
出版年:Mol Cell Oncol
主要な著者: Zhao, Yuhan, Yue, Xuetian, Hu, Wenwei
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905376/
https://ncbi.nlm.nih.gov/pubmed/27308598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1076587
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