The regulation of MDM2 oncogene and its impact on human cancers

Por Zhao, Yuhan, Yu, Haiyang, Hu, Wenwei
Publicado em 2014

Pontin, a novel interactor of mutant p53 that promotes mutant p53 gain of function

Por Zhao, Yuhan, Yue, Xuetian, Hu, Wenwei
Publicado no Mol Cell Oncol (2015)

Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway

Por Li, Lei, Peng, Xin, Guo, Lichun, Zhao, Yuhan, Cheng, Qinghong
Publicado no Int J Clin Exp Pathol (2020)

Mutant p53 in cancer: accumulation, gain-of-function and therapy

Por Yue, Xuetian, Zhao, Yuhan, Xu, Yang, Zheng, Min, Feng, Zhaohui, Hu, Wenwei
Publicado no J Mol Biol (2017)

Metadherin Mediates Lipopolysaccharide-Induced Migration and Invasion of Breast Cancer Cells

Por Zhao, Yuhan, Kong, Xiaoli, Li, Xiaoyan, Yan, Shi, Yuan, Cunzhong, Hu, Wenwei, Yang, Qifeng
Publicado em 2011

Leukemia inhibitory factor promotes EMT through STAT3-dependent miR-21 induction

Por Yue, Xuetian, Zhao, Yuhan, Zhang, Cen, Li, Jun, Liu, Zhen, Liu, Juan, Hu, Wenwei
Publicado no Oncotarget (2015)

A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis

Por Yue, Xuetian, Zhao, Yuhan, Huang, Grace, Li, Jun, Zhu, Junlan, Feng, Zhaohui, Hu, Wenwei
Publicado no Cell Discov (2016)

Extraction, Purification, and Hydrolysis Behavior of Apigenin-7-O-Glucoside from Chrysanthemum Morifolium Tea

Por Wang, Yuxiao, Xu, Zhenzhen, Huang, Yuqi, Wen, Xin, Wu, Yue, Zhao, Yuhan, Ni, Yuanying
Publicado no Molecules (2018)

HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells

Por Wu, Lihua, Yu, Haiyang, Zhao, Yuhan, Zhang, Cen, Wang, Jiabei, Yue, Xuetian, Yang, Qifeng, Hu, Wenwei
Publicado no Oncotarget (2015)

Spliced MDM2 isoforms promote mutant p53 accumulation and gain-of-function in tumorigenesis

Por Zheng, Tongsen, Wang, Jiabei, Zhao, Yuhan, Zhang, Cen, Lin, Meihua, Wang, Xiaowen, Yu, Haiyang, Liu, Lianxin, Feng, Zhaohui, Hu, Wenwei
Publicado em 2013

Identification, validation, and targeting of the mutant p53-PARP-MCM chromatin axis in triple negative breast cancer

Por Qiu, Wei-Gang, Polotskaia, Alla, Xiao, Gu, Di, Lia, Zhao, Yuhan, Hu, Wenwei, Philip, John, Hendrickson, Ronald C., Bargonetti, Jill
Publicado no NPJ Breast Cancer (2017)

A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models

Por Zhao, Yuhan, Wu, Lihua, Yue, Xuetian, Zhang, Cen, Wang, Jianming, Li, Jun, Sun, Xiaohui, Zhu, Yiming, Feng, Zhaohui, Hu, Wenwei
Publicado no eLife (2018)

Chronic restraint stress attenuates p53 function and promotes tumorigenesis

Por Feng, Zhaohui, Liu, Lianxin, Zhang, Cen, Zheng, Tongsen, Wang, Jiabei, Lin, Meihua, Zhao, Yuhan, Wang, Xiaowen, Levine, Arnold J., Hu, Wenwei
Publicado em 2012

Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma

Por Liu, Juan, Zhang, Cen, Lin, Meihua, Zhu, Wei, Liang, Yingjian, Hong, Xuehui, Zhao, Yuhan, Young, Ken H., Hu, Wenwei, Feng, Zhaohui
Publicado em 2014

Autophagy promotes mammalian survival by suppressing oxidative stress and p53

Por Yang, Yang, Karsli-Uzunbas, Gizem, Poillet-Perez, Laura, Sawant, Akshada, Hu, Zhixian Sherrie, Zhao, Yuhan, Moore, Dirk, Hu, Wenwei, White, Eileen
Publicado no Genes Dev (2020)

BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function

Por Yue, Xuetian, Zhao, Yuhan, Liu, Juan, Zhang, Cen, Yu, Haiyang, Wang, Jiabei, Zheng, Tongsen, Liu, Lianxin, Li, Jun, Feng, Zhaohui, Hu, Wenwei
Publicado no eLife (2015)

LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome

Por Wang, Huaying, Wang, Jianming, Zhao, Yuhan, Zhang, Xiao, Liu, Juan, Zhang, Cen, Haffty, Bruce, Verzi, Michael, Zhang, Lanjing, Gao, Nan, Feng, Zhaohui, Hu, Wenwei
Publicado no Cell Death Dis (2020)

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway

Por Li, Xiaoyan, Yang, Qifeng, Yu, Haiyang, Wu, Lihua, Zhao, Yuhan, Zhang, Cen, Yue, Xuetian, Liu, Zhen, Wu, Hao, Haffty, Bruce G., Feng, Zhaohui, Hu, Wenwei
Publicado em 2014

Tumor-Associated Mutant p53 Drives the Warburg Effect

Por Zhang, Cen, Liu, Juan, Liang, Yingjian, Wu, Rui, Zhao, Yuhan, Hong, Xuehui, Lin, Meihua, Yu, Haiyang, Liu, Lianxin, Levine, Arnold J., Hu, Wenwei, Feng, Zhaohui
Publicado em 2013

microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis

Por Zhang, Cen, Liu, Juan, Tan, Chunwen, Yue, Xuetian, Zhao, Yuhan, Peng, Jiaping, Wang, Xiaolong, Laddha, Saurabh V., Chan, Chang S., Zheng, Shu, Hu, Wenwei, Feng, Zhaohui
Publicado no Oncotarget (2016)