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Pontin, a novel interactor of mutant p53 that promotes mutant p53 gain of function
Many tumor-associated mutant p53 proteins gain new activities to promote tumorigenesis, which is termed as gain of function of mutant p53 (GOF). Currently, the mechanisms of mutant p53 GOF remain elusive. We recently identified the AAA+ ATPase pontin as a critical regulator of mutant p53 GOF, thus p...
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| Опубликовано в: : | Mol Cell Oncol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905376/ https://ncbi.nlm.nih.gov/pubmed/27308598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1076587 |
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