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Rational development of a potent 15-lipoxygenase-1 inhibitor with in vitro and ex vivo anti-inflammatory properties
Human 15-lipoxygenase-1 (h-15-LOX-1) is an important mammalian lipoxygenase and plays an important role in several inflammatory lung diseases such as asthma, COPD and chronic bronchitis. Novel potent inhibitors of h-15-LOX-1 are required to explore the role of this enzyme further and to enable drug...
में बचाया:
| में प्रकाशित: | J Med Chem |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872822/ https://ncbi.nlm.nih.gov/pubmed/26331552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01121 |
| टैग : |
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