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Activity-Based Probes for 15-lipoxygenase-1

Human 15-lipoxygenase-1 (15-LOX-1) plays an important role in several inflammatory lung diseases such as asthma, COPD and chronic bronchitis as well as in various CNS diseases like Alzheimer’s, Parkinson’s and stroke. Activity-based probes of 15-LOX-1 are required to explore the role of this enzyme...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Eleftheriadis, Nikolaos, Thee, Stephanie A., Zwinderman, Martijn R. H., Leus, Niek G. J., Dekker, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218545/
https://ncbi.nlm.nih.gov/pubmed/27612308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201606876
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