Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity

[Image: see text] Various mechanisms for regulated cell death include the formation of oxidative mediators such as lipid peroxides and nitric oxide (NO). In this respect, 15-lipoxygenase-1 (15-LOX-1) is a key enzyme that catalyzes the formation of lipid peroxides. The actions of these peroxides are...

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Xehetasun bibliografikoak
Argitaratua izan da:J Med Chem
Egile Nagusiak: Guo, Hao, Verhoek, Iris C., Prins, Gerian G. H., van der Vlag, Ramon, van der Wouden, Petra E., van Merkerk, Ronald, Quax, Wim J., Olinga, Peter, Hirsch, Anna K. H., Dekker, Frank J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2019
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511944/
https://ncbi.nlm.nih.gov/pubmed/30964295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b00212
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