Loading...

Export of Precursor tRNA(Ile) from the Nucleus to the Cytoplasm in Human Cells

In the current concept, tRNA maturation in vertebrate cells, including splicing of introns, trimming of 5’ leader and 3’ trailer, and adding of CCA, is thought to occur exclusively in the nucleus. Here we provide evidence to challenge this concept. Unspliced intron-containing precursor tRNA(Ile) was...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Wei, Min, Zhao, Xia, Liu, Mi, Niu, Meijuan, Seif, Elias, Kleiman, Lawrence
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839721/
https://ncbi.nlm.nih.gov/pubmed/27101286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154044
Tags: Add Tag
No Tags, Be the first to tag this record!