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Export of Precursor tRNA(Ile) from the Nucleus to the Cytoplasm in Human Cells

In the current concept, tRNA maturation in vertebrate cells, including splicing of introns, trimming of 5’ leader and 3’ trailer, and adding of CCA, is thought to occur exclusively in the nucleus. Here we provide evidence to challenge this concept. Unspliced intron-containing precursor tRNA(Ile) was...

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Publicado en:PLoS One
Autores principales: Wei, Min, Zhao, Xia, Liu, Mi, Niu, Meijuan, Seif, Elias, Kleiman, Lawrence
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839721/
https://ncbi.nlm.nih.gov/pubmed/27101286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154044
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