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Export of Precursor tRNA(Ile) from the Nucleus to the Cytoplasm in Human Cells

In the current concept, tRNA maturation in vertebrate cells, including splicing of introns, trimming of 5’ leader and 3’ trailer, and adding of CCA, is thought to occur exclusively in the nucleus. Here we provide evidence to challenge this concept. Unspliced intron-containing precursor tRNA(Ile) was...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wei, Min, Zhao, Xia, Liu, Mi, Niu, Meijuan, Seif, Elias, Kleiman, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839721/
https://ncbi.nlm.nih.gov/pubmed/27101286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154044
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