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Annealing to sequences within the primer binding site loop promotes an HIV-1 RNA conformation favoring RNA dimerization and packaging

The 5′ untranslated region (5′ UTR) of HIV-1 genomic RNA (gRNA) includes structural elements that regulate reverse transcription, transcription, translation, tRNA(Lys3) annealing to the gRNA, and gRNA dimerization and packaging into viruses. It has been reported that gRNA dimerization and packaging...

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Detalhes bibliográficos
Main Authors: Seif, Elias, Niu, Meijuan, Kleiman, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854529/
https://ncbi.nlm.nih.gov/pubmed/23960173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.038497.113
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