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Annealing to sequences within the primer binding site loop promotes an HIV-1 RNA conformation favoring RNA dimerization and packaging

The 5′ untranslated region (5′ UTR) of HIV-1 genomic RNA (gRNA) includes structural elements that regulate reverse transcription, transcription, translation, tRNA(Lys3) annealing to the gRNA, and gRNA dimerization and packaging into viruses. It has been reported that gRNA dimerization and packaging...

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Detaylı Bibliyografya
Asıl Yazarlar: Seif, Elias, Niu, Meijuan, Kleiman, Lawrence
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854529/
https://ncbi.nlm.nih.gov/pubmed/23960173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.038497.113
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