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Ability of Wild-Type and Mutant Lysyl-tRNA Synthetase To Facilitate tRNA(Lys) Incorporation into Human Immunodeficiency Virus Type 1

The major human tRNA(Lys) isoacceptors, tRNA1,2Lys and tRNA3Lys, are selectively packaged into human immunodeficiency virus type 1 (HIV-1) during assembly, where tRNA3Lys acts as a primer for reverse transcription. Lysyl-tRNA synthetase (LysRS) is also incorporated into HIV-1, independently of tRNA(...

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Udgivet i:J Virol
Principais autores: Cen, Shan, Javanbakht, Hassan, Niu, Meijuan, Kleiman, Lawrence
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321381/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14722314/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.3.1595-1601.2004
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