Ability of Wild-Type and Mutant Lysyl-tRNA Synthetase To Facilitate tRNA(Lys) Incorporation into Human Immunodeficiency Virus Type 1

The major human tRNA(Lys) isoacceptors, tRNA1,2Lys and tRNA3Lys, are selectively packaged into human immunodeficiency virus type 1 (HIV-1) during assembly, where tRNA3Lys acts as a primer for reverse transcription. Lysyl-tRNA synthetase (LysRS) is also incorporated into HIV-1, independently of tRNA(...

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Detalhes bibliográficos
Main Authors: Cen, Shan, Javanbakht, Hassan, Niu, Meijuan, Kleiman, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321381/
https://ncbi.nlm.nih.gov/pubmed/14722314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.3.1595-1601.2004
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