Ability of Wild-Type and Mutant Lysyl-tRNA Synthetase To Facilitate tRNA(Lys) Incorporation into Human Immunodeficiency Virus Type 1

The major human tRNA(Lys) isoacceptors, tRNA1,2Lys and tRNA3Lys, are selectively packaged into human immunodeficiency virus type 1 (HIV-1) during assembly, where tRNA3Lys acts as a primer for reverse transcription. Lysyl-tRNA synthetase (LysRS) is also incorporated into HIV-1, independently of tRNA(...

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Pubblicato in:	J Virol
Autori principali:	Cen, Shan, Javanbakht, Hassan, Niu, Meijuan, Kleiman, Lawrence
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321381/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14722314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.3.1595-1601.2004
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