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Roles of the Linker Region of RNA Helicase A in HIV-1 RNA Metabolism

RNA helicase A (RHA) promotes multiple steps in HIV-1 production including transcription and translation of viral RNA, annealing of primer tRNA(Lys3) to viral RNA, and elevating the ratio of unspliced to spliced viral RNA. At its amino terminus are two double-stranded RNA binding domains (dsRBDs) th...

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Detalles Bibliográficos
Main Authors: Xing, Li, Niu, Meijuan, Zhao, Xia, Kleiman, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819368/
https://ncbi.nlm.nih.gov/pubmed/24223160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078596
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