Targeting mTOR and p53 signaling inhibits muscle invasive bladder cancer in vivo

Urothelial tumors, accompanied by mutations of the tumor suppressor protein TP53 and dysregulation of mTOR signaling, are frequently associated with aggressive growth and invasiveness. We investigated whether targeting these two pathways would inhibit urothelial tumor growth and progression. Six-wee...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Prev Res (Phila)
Asıl Yazarlar: Madka, Venkateshwar, Mohammed, Altaf, Li, Qian, Zhang, Yuting, Biddick, Laura, Patlolla, Jagan M.R., Lightfoot, Stan, Towner, Rheal A., Wu, Xue-Ru, Steele, Vernon E., Kopelovich, Levy, Rao, Chinthalapally V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839263/
https://ncbi.nlm.nih.gov/pubmed/26577454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-15-0199
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller