Design, Synthesis, Cytotoxic Activity and Molecular Docking Studies of New 20(S)-Sulfonylamidine Camptothecin Derivatives

In an ongoing investigation of 20-sulfonylamidine derivatives (9, YQL-9a) of camptothecin (1) as potential anticancer agents directly and selectively inhibiting topoisomerase (Topo) I, the sulfonylamidine pharmacophore was held constant, and a camptothecin derivatives with various substitution patte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Med Chem
Egile Nagusiak: Song, Zi-Long, Wang, Mei-Juan, Li, Lanlan, Wu, Dan, Wang, Yu-Han, Yan, Li-Ting, Morris-Natschke, Susan L., Liu, Ying-Qian, Zhao, Yong-Long, Wang, Chih-Ya, Liu, Huanxiang, Goto, Masuo, Liu, Heng, Zhu, Gao-Xiang, Lee, Kuo-Hsiung
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834258/
https://ncbi.nlm.nih.gov/pubmed/26994847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.02.070
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak