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Adenosine A(1) Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea

Cisplatin is a commonly used antineoplastic agent that produces ototoxicity that is mediated in part by increasing levels of reactive oxygen species (ROS) via the NOX3 NADPH oxidase pathway in the cochlea. Recent studies implicate ROS generation in mediating inflammatory and apoptotic processes and...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Kaur, Tejbeer, Borse, Vikrant, Sheth, Sandeep, Sheehan, Kelly, Ghosh, Sumana, Tupal, Srinivasan, Jajoo, Sarvesh, Mukherjea, Debashree, Rybak, Leonard P., Ramkumar, Vickram
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821909/
https://ncbi.nlm.nih.gov/pubmed/27053204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3111-15.2016
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