Adenosine A(1) Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea

Cisplatin is a commonly used antineoplastic agent that produces ototoxicity that is mediated in part by increasing levels of reactive oxygen species (ROS) via the NOX3 NADPH oxidase pathway in the cochlea. Recent studies implicate ROS generation in mediating inflammatory and apoptotic processes and...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Kaur, Tejbeer, Borse, Vikrant, Sheth, Sandeep, Sheehan, Kelly, Ghosh, Sumana, Tupal, Srinivasan, Jajoo, Sarvesh, Mukherjea, Debashree, Rybak, Leonard P., Ramkumar, Vickram
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2016
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821909/
https://ncbi.nlm.nih.gov/pubmed/27053204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3111-15.2016
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