Yüklüyor......

Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2

Both orthosteric and allosteric antagonists of the group II metabotropic glutamate receptors (mGlus) have been used to establish a link between mGlu(2/3) inhibition and a variety of CNS diseases and disorders. Though these tools typically have good selectivity for mGlu(2/3) versus the remaining six...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Med Chem
Asıl Yazarlar: Felts, Andrew S., Rodriguez, Alice L., Smith, Katrina A., Engers, Julie L., Morrison, Ryan D., Byers, Frank W., Blobaum, Anna L., Locuson, Charles W., Chang, Sichen, Venable, Daryl F., Niswender, Colleen M., Daniels, J. Scott, Conn, P. Jeffrey, Lindsley, Craig W., Emmitte, Kyle A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817271/
https://ncbi.nlm.nih.gov/pubmed/26524606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01371
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!