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A Novel Class of Succinimide-Derived Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 1 Provides Insight into a Disconnect in Activity between the Rat and Human Receptors
[Image: see text] Recent progress in the discovery of mGlu(1) allosteric modulators has suggested the modulation of mGlu(1) could offer possible treatment for a number of central nervous system disorders; however, the available chemotypes are inadequate to fully investigate the therapeutic potential...
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| Główni autorzy: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2014
|
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102972/ https://ncbi.nlm.nih.gov/pubmed/24798819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn5000343 |
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