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A Potent, Selective and Cell-active Inhibitor of Human Type I Protein Arginine Methyltransferases
Protein arginine methyltransferases (PRMTs) play a crucial role in a variety of biological processes. Overexpression of PRMTs has been implicated in various human diseases including cancer. Consequently, selective small-molecule inhibitors of PRMTs have been pursued by both academia and pharmaceutic...
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| I publikationen: | ACS Chem Biol |
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| Huvudupphovsmän: | , , , , , , , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4798913/ https://ncbi.nlm.nih.gov/pubmed/26598975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00839 |
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