Partial mGlu(5) Negative Allosteric Modulators Attenuate Cocaine-Mediated Behaviors and Lack Psychotomimetic-Like Effects

Cocaine abuse remains a public health concern for which pharmacotherapies are largely ineffective. Comorbidities between cocaine abuse, depression, and anxiety support the development of novel treatments targeting multiple symptom clusters. Selective negative allosteric modulators (NAMs) targeting t...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Gould, Robert W, Amato, Russell J, Bubser, Michael, Joffe, Max E, Nedelcovych, Michael T, Thompson, Analisa D, Nickols, Hilary H, Yuh, Johannes P, Zhan, Xiaoyan, Felts, Andrew S, Rodriguez, Alice L, Morrison, Ryan D, Byers, Frank W, Rook, Jerri M, Daniels, John S, Niswender, Colleen M, Conn, P Jeffrey, Emmitte, Kyle A, Lindsley, Craig W, Jones, Carrie K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748441/
https://ncbi.nlm.nih.gov/pubmed/26315507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.265
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