Differential Pharmacology and Binding of mGlu(2) Receptor Allosteric Modulators

Allosteric modulation of metabotropic glutamate receptor 2 (mGlu(2)) has demonstrated efficacy in preclinical rodent models of several brain disorders, leading to industry and academic drug discovery efforts. Although the pharmacology and binding sites of some mGlu(2) allosteric modulators have been...

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Bibliografiske detaljer
Udgivet i:Mol Pharmacol
Main Authors: O’Brien, Daniel E., Shaw, Douglas M., Cho, Hyekyung P., Cross, Alan J., Wesolowski, Steven S., Felts, Andrew S., Bergare, Jonas, Elmore, Charles S., Lindsley, Craig W., Niswender, Colleen M., Conn, P. Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894801/
https://ncbi.nlm.nih.gov/pubmed/29545267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.110114
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