Differential Pharmacology and Binding of mGlu(2) Receptor Allosteric Modulators

Allosteric modulation of metabotropic glutamate receptor 2 (mGlu(2)) has demonstrated efficacy in preclinical rodent models of several brain disorders, leading to industry and academic drug discovery efforts. Although the pharmacology and binding sites of some mGlu(2) allosteric modulators have been...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: O’Brien, Daniel E., Shaw, Douglas M., Cho, Hyekyung P., Cross, Alan J., Wesolowski, Steven S., Felts, Andrew S., Bergare, Jonas, Elmore, Charles S., Lindsley, Craig W., Niswender, Colleen M., Conn, P. Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894801/
https://ncbi.nlm.nih.gov/pubmed/29545267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.110114
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