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mGlu(5) Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu(5)-Endocannabinoid Signaling
[Image: see text] Metabotropic glutamate (mGlu) receptor type 5 (mGlu(5)) positive allosteric modulators (PAMs) enhance hippocampal long-term potentiation (LTP) and have cognition-enhancing effects in animal models. These effects were initially thought to be mediated by potentiation of mGlu(5) modul...
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| Vydáno v: | ACS Pharmacol Transl Sci |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American
Chemical Society
2019
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591772/ https://ncbi.nlm.nih.gov/pubmed/31259318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00017 |
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