Differential Pharmacology and Binding of mGlu(2) Receptor Allosteric Modulators

Allosteric modulation of metabotropic glutamate receptor 2 (mGlu(2)) has demonstrated efficacy in preclinical rodent models of several brain disorders, leading to industry and academic drug discovery efforts. Although the pharmacology and binding sites of some mGlu(2) allosteric modulators have been...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Pharmacol
Main Authors: O’Brien, Daniel E., Shaw, Douglas M., Cho, Hyekyung P., Cross, Alan J., Wesolowski, Steven S., Felts, Andrew S., Bergare, Jonas, Elmore, Charles S., Lindsley, Craig W., Niswender, Colleen M., Conn, P. Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2018
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894801/
https://ncbi.nlm.nih.gov/pubmed/29545267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.110114
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