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AlkB homolog 2 (ABH2) mediated repair of ethenoadenine lesions in mammalian DNA
Endogenous formation of the mutagenic DNA adduct 1,N(6)-ethenoadenosine (εA) originates from lipid peroxidation. Elevated levels of εA in cancer-prone tissues suggest a role for this adduct in the development of some cancers. The base excision repair (BER) pathway has been considered the principal r...
Guardat en:
Publicat a: | Cancer Res |
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Autors principals: | , , , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2008
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725713/ https://ncbi.nlm.nih.gov/pubmed/18519673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0796 |
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