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Substrate specificities of bacterial and human AlkB proteins
Methylating agents introduce cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) residues into nucleic acids, and it was recently demonstrated that the Escherichia coli AlkB protein and two human homologues, hABH2 and hABH3, can remove these lesions from DNA by oxidative demethylation. Mo...
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| izdano v: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15229293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh655 |
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