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Substrate specificities of bacterial and human AlkB proteins

Methylating agents introduce cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) residues into nucleic acids, and it was recently demonstrated that the Escherichia coli AlkB protein and two human homologues, hABH2 and hABH3, can remove these lesions from DNA by oxidative demethylation. Mo...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Nucleic Acids Res
Príomhchruthaitheoirí: Falnes, Pål Ø., Bjørås, Magnar, Aas, Per Arne, Sundheim, Ottar, Seeberg, Erling
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Oxford University Press 2004
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15229293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh655
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