Substrate specificities of bacterial and human AlkB proteins

Methylating agents introduce cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) residues into nucleic acids, and it was recently demonstrated that the Escherichia coli AlkB protein and two human homologues, hABH2 and hABH3, can remove these lesions from DNA by oxidative demethylation. Mo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Falnes, Pål Ø., Bjørås, Magnar, Aas, Per Arne, Sundheim, Ottar, Seeberg, Erling
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2004
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15229293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh655
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