Substrate specificities of bacterial and human AlkB proteins

Methylating agents introduce cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) residues into nucleic acids, and it was recently demonstrated that the Escherichia coli AlkB protein and two human homologues, hABH2 and hABH3, can remove these lesions from DNA by oxidative demethylation. Mo...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Falnes, Pål Ø., Bjørås, Magnar, Aas, Per Arne, Sundheim, Ottar, Seeberg, Erling
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15229293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh655
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