Substrate specificities of bacterial and human AlkB proteins

Methylating agents introduce cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) residues into nucleic acids, and it was recently demonstrated that the Escherichia coli AlkB protein and two human homologues, hABH2 and hABH3, can remove these lesions from DNA by oxidative demethylation. Mo...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Falnes, Pål Ø., Bjørås, Magnar, Aas, Per Arne, Sundheim, Ottar, Seeberg, Erling
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2004
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15229293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh655
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