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Substrate specificities of bacterial and human AlkB proteins

Methylating agents introduce cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) residues into nucleic acids, and it was recently demonstrated that the Escherichia coli AlkB protein and two human homologues, hABH2 and hABH3, can remove these lesions from DNA by oxidative demethylation. Mo...

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Falnes, Pål Ø., Bjørås, Magnar, Aas, Per Arne, Sundheim, Ottar, Seeberg, Erling
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15229293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh655
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