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AlkB homolog 2 (ABH2) mediated repair of ethenoadenine lesions in mammalian DNA
Endogenous formation of the mutagenic DNA adduct 1,N(6)-ethenoadenosine (εA) originates from lipid peroxidation. Elevated levels of εA in cancer-prone tissues suggest a role for this adduct in the development of some cancers. The base excision repair (BER) pathway has been considered the principal r...
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| Publicado no: | Cancer Res |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725713/ https://ncbi.nlm.nih.gov/pubmed/18519673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0796 |
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