MUC1 Vaccines, Comprised of Glycosylated or Non-Glycosylated Peptides or Tumor-Derived MUC1, Can Circumvent Immunoediting to Control Tumor Growth in MUC1 Transgenic Mice

It remains challenging to produce decisive vaccines against MUC1, a tumor-associated antigen widely expressed by pancreas, breast and other tumors. Employing clinically relevant mouse models, we ruled out such causes as irreversible T-cell tolerance, inadequate avidity, and failure of T-cells to rec...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Lakshminarayanan, Vani, Supekar, Nitin T., Wei, Jie, McCurry, Dustin B., Dueck, Amylou C., Kosiorek, Heidi E., Trivedi, Priyanka P., Bradley, Judy M., Madsen, Cathy S., Pathangey, Latha B., Hoelzinger, Dominique B., Wolfert, Margreet A., Boons, Geert-Jan, Cohen, Peter A., Gendler, Sandra J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720451/
https://ncbi.nlm.nih.gov/pubmed/26788922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145920
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares