MUC1 Vaccines, Comprised of Glycosylated or Non-Glycosylated Peptides or Tumor-Derived MUC1, Can Circumvent Immunoediting to Control Tumor Growth in MUC1 Transgenic Mice

It remains challenging to produce decisive vaccines against MUC1, a tumor-associated antigen widely expressed by pancreas, breast and other tumors. Employing clinically relevant mouse models, we ruled out such causes as irreversible T-cell tolerance, inadequate avidity, and failure of T-cells to rec...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Lakshminarayanan, Vani, Supekar, Nitin T., Wei, Jie, McCurry, Dustin B., Dueck, Amylou C., Kosiorek, Heidi E., Trivedi, Priyanka P., Bradley, Judy M., Madsen, Cathy S., Pathangey, Latha B., Hoelzinger, Dominique B., Wolfert, Margreet A., Boons, Geert-Jan, Cohen, Peter A., Gendler, Sandra J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720451/
https://ncbi.nlm.nih.gov/pubmed/26788922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145920
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