Immune and Anticancer Responses Elicited by Fully Synthetic Aberrantly Glycosylated MUC1 Tripartite Vaccines Modified by a TLR2 or TLR9 Agonist

The mucin MUC1 is overexpressed and aberrantly glycosylated by many epithelial cancer cells manifested by truncated O-linked saccharides. Although tumor-associated MUC1 has generated considerable attention because of its potential for the development of a therapeutic cancer vaccine, it has been diff...

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Main Authors: Abdel-Aal, Abu-Baker M., Lakshminarayanan, Vani, Thompson, Pamela, Supekar, Nitin, Bradley, Judy M., Wolfert, Margreet A., Cohen, Peter A., Gendler, Sandra J., Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113397/
https://ncbi.nlm.nih.gov/pubmed/24890740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402077
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