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Robust immune responses elicited by a fully synthetic three-component vaccine

The over-expression of saccharides such as Globo-H, Lewis(Y) and Tn antigen is a common feature of oncogenic transformed cells. Endeavors to exploit this aberrant glycosylation for cancer vaccine development has been complicated by difficulties of eliciting high titers of IgG antibodies against clas...

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Detalhes bibliográficos
Main Authors: Ingale, Sampat, Wolfert, Margreet A., Gaekwad, Jidnyasa, Buskas, Therese, Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836923/
https://ncbi.nlm.nih.gov/pubmed/17767155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2007.25
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