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Modulation of Innate Immune Responses with Synthetic Lipid A Derivatives

The lipid A moiety of lipopolysaccharides (LPS) initiates innate immune responses by interacting with Toll-like receptor 4 (TLR4) which results in the production of a wide range of cytokines. Derivatives of lipid A show potential for use as immuno-modulators for the treatment of a wide range of dise...

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Bibliografske podrobnosti
Main Authors: Zhang, Yanghui, Gaekwad, Jidnyasa, Wolfert, Margreet A., Boons, Geert-Jan
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529018/
https://ncbi.nlm.nih.gov/pubmed/17391035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja068922a
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